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Prominent Ailments: 4 Highest Ranked Incurable Diseases

Even though modern medicine has made breakthrough to eradicate and cure some prominent ailments – it has however failed to cure the common flu suffered by many people in the world every year. 

The most ranked incurable diseases are:

Ebola is a virus belonging to the Filoviridae family that is responsible for a severe and often fatal viral hemorrhagic fever. 

Outbreaks in primates such as gorillas and chimpanzees as well as humans have been recorded. 
Ebola Victim 

The disease is evidenced by extreme fever, rash – and prolific hemorrhaging resulting in high human fatality ranging from 50 to 90 percent. 

Deriving its name from the Ebola River in the northern Congo basin of central Africa, where it first emerged in 1976. 

Ebola is closely related to the Marburg virus discovered in 1967. The duo is the only members of the Filoviridae that cause epidemic human disease. The third – Ebola Reston is not deadly to humanity.

The full name is poliomyelitis or infantile paralysis. It is an acute viral infectious disease of the nervous system that usually manifests itself with common symptoms including: fever, headache, nausea, fatigue and muscle pains. 

This is followed by a more serious and permanent paralysis of muscles in one or more limbs, the throat – or the chest. 

Polio cases are often recorded in children below five years. 90 percent of infected patients show no signs of illness at all while 5 to 10 percent show symptoms. Polio has no cure. Polio has been eliminated from most of the world – and is now endemic only in Africa and India.


Also known as flu – it is an acute viral infection of the upper or lower respiratory tract that is marked by fever, chills – and a weakness and pain in the muscles, coupled with changeable degrees of head and abdomen pain. 

Influenza is caused by any of several strains of orthomyxoviruses. The three major types generally produce similar symptoms but are totally unrelated – so that infection with one type confers no immunity against the others. 

The A viruses cause the great influenza epidemics, and the B viruses cause smaller localised outbreaks – the C viruses does not affect humans.

Creutzfeldt-Jakob Disease

First described in the 1920s by the German neurologists Hans Gerhard Creutzfeldt and Alfons Maria Jakob, the disease is similar to other neurodegenerative ailment such as kuru and scrapie – which occurs in sheep and goats. 

The three diseases are characterised by spongelike pattern of neuronal destruction leaving brain tissue filled with holes. Creutzfeldt-Jakob disease is a rare fatal degenerative disease of the central nervous system affecting 1 person in a million – and common in adults between 40 and 70 years. 

Symptoms include vague behavioral changes, abnormal vision and involuntary movements. The disease claims a victim within a year – and there is no known cure. - Online Sources 

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